Cloned transcription factor MTF-1 activates the mouse metallothionein I promoter.

Metallothioneins (MTs) are small cysteine-rich proteins whose structure is conserved from fungi to man. MTs strongly bind heavy metals, notably zinc, copper and cadmium. Upon exposure of cells to heavy metal and other adverse treatments, MT gene transcription is strongly enhanced. Metal induction is...

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Autores principales: Radtke, F, Heuchel, R, Georgiev, O, Hergersberg, M, Gariglio, M, Dembic, Z, Schaffner, W
Formato: Artigo
Lenguaje:Inglês
Publicado: 1993
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC413347/
https://ncbi.nlm.nih.gov/pubmed/8467794
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