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Cadherin Cytoplasmic Domains Inhibit the Cell Surface Localization of Endogenous E-Cadherin, Blocking Desmosome and Tight Junction Formation and Inducing Cell Dissociation

The downregulation of E-cadherin function has fundamental consequences with respect to cancer progression, and occurs as part of the epithelial–mesenchymal transition (EMT). In this study, we show that the expression of the Discosoma sp. red fluorescent protein (DsRed)-tagged cadherin cytoplasmic do...

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Bibliografske podrobnosti
Main Authors: Ozawa, Masayuki, Kobayashi, Wakako
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133371/
https://ncbi.nlm.nih.gov/pubmed/25121615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105313
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