Enhanced Early Innate and T Cell-mediated Responses in Subjects Immunized with Anthrax Vaccine Adsorbed Plus CPG 7909 (AV7909)

NuThrax(™) (Anthrax Vaccine Adsorbed with CPG 7909 Adjuvant) (AV7909) is in development. Samples obtained in a Phase Ib clinical trial were tested to confirm biomarkers of innate immunity and evaluate effects of CPG 7909 (PF-03512676) on adaptive immunity. Subjects received two intramuscular doses o...

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Hlavní autoři: Minang, Jacob T., Inglefield, Jon R., Harris, Andrea M., Lathey, Janet L., Alleva, David G., Sweeney, Diane L., Hopkins, Robert J, Lacy, Michael J., Bernton, Edward W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133324/
https://ncbi.nlm.nih.gov/pubmed/24530403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2014.01.096
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