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Gearing up chromatin: A role for chromatin remodeling during the transcriptional restart upon DNA damage

During transcription, RNA polymerase may encounter DNA lesions, which causes stalling of transcription. To overcome the RNA polymerase blocking lesions, the transcribed strand is repaired by a dedicated repair mechanism, called transcription coupled nucleotide excision repair (TC-NER). After repair...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mandemaker, Imke K, Vermeulen, Wim, Marteijn, Jurgen A
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133215/
https://ncbi.nlm.nih.gov/pubmed/24809693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/nucl.29085
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