Subverting ER-Stress towards Apoptosis by Nelfinavir and Curcumin Coexposure Augments Docetaxel Efficacy in Castration Resistant Prostate Cancer Cells

Despite its side-effects, docetaxel (DTX) remains a first-line treatment against castration resistant prostate cancer (CRPC). Therefore, strategies to increase its anti-tumor efficacy and decrease its side effects are critically needed. Targeting of the constitutive endoplasmic reticulum (ER) stress...

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Detalhes bibliográficos
Main Authors: Mathur, Aditi, Abd Elmageed, Zakaria Y., Liu, Xichun, Kostochka, Mikhail L., Zhang, Haitao, Abdel-Mageed, Asim B., Mondal, Debasis
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133210/
https://ncbi.nlm.nih.gov/pubmed/25121735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0103109
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