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A Switch in Pathogenic Mechanism in Myelin Oligodendrocyte Glycoprotein-Induced EAE in GILT-Free Mice
Gamma interferon-inducible lysosomal thiol reductase (GILT) is an enzyme located in the Lamp-2 positive compartments of antigen presenting cells. GILT(−/−) mice are phenotypically normal but their T cells exhibit reduced proliferation to several exogenously administered antigens that include cystein...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4133136/ https://ncbi.nlm.nih.gov/pubmed/22586035 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101898 |
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