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A Switch in Pathogenic Mechanism in Myelin Oligodendrocyte Glycoprotein-Induced EAE in GILT-Free Mice

Gamma interferon-inducible lysosomal thiol reductase (GILT) is an enzyme located in the Lamp-2 positive compartments of antigen presenting cells. GILT(−/−) mice are phenotypically normal but their T cells exhibit reduced proliferation to several exogenously administered antigens that include cystein...

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Библиографические подробности
Главные авторы: Bergman, Cheryl M., Marta, Cecilia B., Maric, Maja, Pfeiffer, Steven E., Cresswell, Peter, Ruddle, Nancy H.
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133136/
https://ncbi.nlm.nih.gov/pubmed/22586035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101898
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