Complementation of antigen presenting cells to generate T lymphocytes with broad target specificity

Antigen-specific T-cells provide a therapy for cancer that is highly specific, self-replicating and potentially devoid of toxicity. Ideally, tumor-specific T-cells should recognize multiple epitopes on multiple antigens to prevent tumor immune-escape. However the large-scale expansion of such broad-...

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Detalhes bibliográficos
Main Authors: Ngo, Minhtran C, Ando, Jun, Leen, Ann M, Ennamuri, Sravya, Lapteva, Natalia, Vera, Juan F, Min-Venditti, Amelia, Mims, Martha P, Heslop, Helen E, Bollard, Catherine M, Gottschalk, Stephen, Rooney, Cliona M
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133102/
https://ncbi.nlm.nih.gov/pubmed/24714353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0000000000000014
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