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Stably maintained microdomain of localized unrestrained supercoiling at a Drosophila heat shock gene locus.

A psoralen crosslinking assay was utilized to detect localized, unrestrained DNA supercoiling (torsional tension) in vivo in Drosophila chromosomal regions subject to differential transcriptional activity. By comparing rates of crosslinking in intact cells with those in cells where potential tension...

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Publicat a:EMBO J
Autors principals: Jupe, E R, Sinden, R R, Cartwright, I L
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1993
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC413308/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8458324/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1993.tb05748.x
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