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Transferring the PRIMO Coarse-Grained Force Field to the Membrane Environment: Simulations of Membrane Proteins and Helix–Helix Association

[Image: see text] An extension of the recently developed PRIMO coarse-grained force field to membrane environments, PRIMO-M, is described. The membrane environment is modeled with the heterogeneous dielectric generalized Born (HDGB) methodology that simply replaces the standard generalized Born mode...

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Detalhes bibliográficos
Main Authors: Kar, Parimal, Gopal, Srinivasa Murthy, Cheng, Yi-Ming, Panahi, Afra, Feig, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132866/
https://ncbi.nlm.nih.gov/pubmed/25136271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ct500443v
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