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Actin Enables the Antimicrobial Action of LL-37 Peptide in the Presence of Microbial Proteases

Host defense peptides play an important host-protective role by their microcidal action, immunomodulatory functions, and tissue repair activities. Proteolysis is a common strategy of pathogens used to neutralize host defense peptides. Here, we show that actin, the most abundant structural protein in...

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Bibliografische gegevens
Hoofdauteurs: Sol, Asaf, Skvirsky, Yaniv, Nashef, Rizan, Zelentsova, Katya, Burstyn-Cohen, Tal, Blotnick, Edna, Muhlrad, Andras, Bachrach, Gilad
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132794/
https://ncbi.nlm.nih.gov/pubmed/24947511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.579672
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