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Novel K(v)7.1-Phosphatidylinositol 4,5-Bisphosphate Interaction Sites Uncovered by Charge Neutralization Scanning

K(v)7.1 to K(v)7.5 α-subunits belong to the family of voltage-gated potassium channels (K(v)). Assembled with the β-subunit KCNE1, K(v)7.1 conducts the slowly activating potassium current I(Ks), which is one of the major currents underlying repolarization of the cardiac action potential. A known reg...

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Main Authors: Eckey, Karina, Wrobel, Eva, Strutz-Seebohm, Nathalie, Pott, Lutz, Schmitt, Nicole, Seebohm, Guiscard
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132781/
https://ncbi.nlm.nih.gov/pubmed/24947509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.589796
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