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Road rules for traffic on DNA—systematic analysis of transcriptional roadblocking in vivo
Genomic DNA is bound by many proteins that could potentially impede elongation of RNA polymerase (RNAP), but the factors determining the magnitude of transcriptional roadblocking in vivo are poorly understood. Through systematic experiments and modeling, we analyse how roadblocking by the lac repres...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4132739/ https://ncbi.nlm.nih.gov/pubmed/25034688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku627 |
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