Discovery of the β-barrel–type RNA methyltransferase responsible for N(6)-methylation of N(6)-threonylcarbamoyladenosine in tRNAs

Methylation is a versatile reaction involved in the synthesis and modification of biologically active molecules, including RNAs. N(6)-methyl-threonylcarbamoyl adenosine (m(6)t(6)A) is a post-transcriptional modification found at position 37 of tRNAs from bacteria, insect, plants, and mammals. Here,...

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Detalhes bibliográficos
Main Authors: Kimura, Satoshi, Miyauchi, Kenjyo, Ikeuchi, Yoshiho, Thiaville, Patrick C., de Crécy-Lagard, Valérie, Suzuki, Tsutomu
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132733/
https://ncbi.nlm.nih.gov/pubmed/25063302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku618
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