Full-length haplotype reconstruction to infer the structure of heterogeneous virus populations

Next-generation sequencing (NGS) technologies enable new insights into the diversity of virus populations within their hosts. Diversity estimation is currently restricted to single-nucleotide variants or to local fragments of no more than a few hundred nucleotides defined by the length of sequence r...

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Bibliografiska uppgifter
Huvudupphovsmän: Giallonardo, Francesca Di, Töpfer, Armin, Rey, Melanie, Prabhakaran, Sandhya, Duport, Yannick, Leemann, Christine, Schmutz, Stefan, Campbell, Nottania K., Joos, Beda, Lecca, Maria Rita, Patrignani, Andrea, Däumer, Martin, Beisel, Christian, Rusert, Peter, Trkola, Alexandra, Günthard, Huldrych F., Roth, Volker, Beerenwinkel, Niko, Metzner, Karin J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2014
Ämnen:
Methods Online
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132706/
https://ncbi.nlm.nih.gov/pubmed/24972832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku537
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