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Restoration of surface IgM-mediated apoptosis in an anti-IgM-resistant variant of WEHI-231 lymphoma cells by HS1, a protein-tyrosine kinase substrate.

The HS1 protein is one of the major substrates of non-receptor-type protein-tyrosine kinases and is phosphorylated immediately after crosslinking of the surface IgM on B cells. The mouse B-lymphoma cell line WEHI-231 is known to undergo apoptosis upon crosslinking of surface IgM by anti-IgM antibodi...

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Detalhes bibliográficos
Main Authors: Fukuda, T, Kitamura, D, Taniuchi, I, Maekawa, Y, Benhamou, L E, Sarthou, P, Watanabe, T
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC41327/
https://ncbi.nlm.nih.gov/pubmed/7638185
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