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The Yersinia pestis Siderophore, Yersiniabactin, and the ZnuABC system both contribute to Zinc acquisition and the development of lethal septicemic plague in mice

Bacterial pathogens must overcome host sequestration of zinc (Zn(2+)), an essential micronutrient, during the infectious disease process. While the mechanisms to acquire chelated Zn(2+) by bacteria are largely undefined, many pathogens rely upon the ZnuABC family of ABC transporters. Here we show th...

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Main Authors: Bobrov, Alexander G., Kirillina, Olga, Fetherston, Jacqueline D., Miller, M. Clarke, Burlison, Joseph A., Perry, Robert D.
格式: Artigo
語言:Inglês
出版: 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132657/
https://ncbi.nlm.nih.gov/pubmed/24979062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12693
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