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Intrapulmonary lipopolysaccharide exposure upregulates cytokine expression in the neonatal brainstem

Perinatal inflammation and neonatal sepsis trigger lung and brain injury. We hypothesized that endotoxin exposure in the immature lung upregulates proinflammatory cytokine expression in the brainstem and impairs respiratory control. Lipopolysaccharide (LPS) or saline was administered intratracheally...

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Detalhes bibliográficos
Main Authors: Balan, Kannan V, Kc, Prabha, Mayer, Catherine A, Wilson, Christopher G, Belkadi, Abdelmadjid, Martin, Richard J
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132655/
https://ncbi.nlm.nih.gov/pubmed/22176020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1651-2227.2011.02564.x
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