Perforant path synaptic loss correlates with cognitive impairment and Alzheimer's disease in the oldest-old

Alzheimer’s disease, which is defined pathologically by abundant amyloid plaques and neurofibrillary tangles concurrent with synaptic and neuronal loss, is the most common underlying cause of dementia in the elderly. Among the oldest-old, those aged 90 and older, other ageing-related brain pathologi...

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Detalhes bibliográficos
Main Authors: Robinson, John L., Molina-Porcel, Laura, Corrada, Maria M., Raible, Kevin, Lee, Edward B., Lee, Virginia M.-Y., Kawas, Claudia H., Trojanowski, John Q.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132652/
https://ncbi.nlm.nih.gov/pubmed/25012223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awu190
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