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Widespread grey matter pathology dominates the longitudinal cerebral MRI and clinical landscape of amyotrophic lateral sclerosis

Diagnosis, stratification and monitoring of disease progression in amyotrophic lateral sclerosis currently rely on clinical history and examination. The phenotypic heterogeneity of amyotrophic lateral sclerosis, including extramotor cognitive impairments is now well recognized. Candidate biomarkers...

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Detalhes bibliográficos
Main Authors: Menke, Ricarda A. L., Körner, Sonja, Filippini, Nicola, Douaud, Gwenaëlle, Knight, Steven, Talbot, Kevin, Turner, Martin R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132644/
https://ncbi.nlm.nih.gov/pubmed/24951638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awu162
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