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Modifications of transthyretin in amyloid fibrils: analysis of amyloid from homozygous and heterozygous individuals with the Met30 mutation.

The finding of individuals homozygous for FAP I (familial amyloidotic polyneuropathy, transthyretin TTRMet30) with amyloid deposits in the vitreous body, gave us access to a unique material lacking wild type transthyretin and contaminating proteins. Amyloid TTR is modified in several ways. Besides t...

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Detalhes bibliográficos
Main Authors: Thylén, C, Wahlqvist, J, Haettner, E, Sandgren, O, Holmgren, G, Lundgren, E
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC413261/
https://ncbi.nlm.nih.gov/pubmed/8095018
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