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Effector bottleneck: microbial reprogramming of parasitized host cell transcription by epigenetic remodeling of chromatin structure

Obligate intracellular pathogenic bacteria evolved to manipulate their host cells with a limited range of proteins constrained by their compact genomes. The harsh environment of a phagocytic defense cell is one that challenges the majority of commensal and pathogenic bacteria; yet, these are the obl...

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Detalhes bibliográficos
Main Authors: Sinclair, Sara H., Rennoll-Bankert, Kristen E., Dumler, J. S.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132484/
https://ncbi.nlm.nih.gov/pubmed/25177343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2014.00274
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