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Differential Localisation of PARP-1 N-Terminal Fragment in PARP-1(+/+) and PARP-1(−/−) Murine Cells

Human PARP family consists of 17 members of which PARP-1 is a prominent member and plays a key role in DNA repair pathways. It has an N-terminal DNA-binding domain (DBD) encompassing the nuclear localisation signal (NLS), central automodification domain and C-terminal catalytic domain. PARP-1 accoun...

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Bibliografiske detaljer
Main Authors: Rajiah, Ida Rachel, Skepper, Jeremy
Format: Artigo
Sprog:Inglês
Udgivet: Korean Society for Molecular and Cellular Biology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132304/
https://ncbi.nlm.nih.gov/pubmed/25078451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2014.0077
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