Mesenchymal cell interaction with ovarian cancer cells induces a background dependent pro-metastatic transcriptomic profile

BACKGROUND: The cross talk between the stroma and cancer cells plays a major role in phenotypic modulation. During peritoneal carcinomatosis ovarian cancer cells interact with mesenchymal stem cells (MSC) resulting in increased metastatic ability. Understanding the transcriptomic changes underlying...

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Detalhes bibliográficos
Main Authors: Lis, Raphael, Touboul, Cyril, Halabi, Najeeb M, Madduri, Abishek Sainath, Querleu, Denis, Mezey, Jason, Malek, Joel A, Suhre, Karsten, Rafii, Arash
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132214/
https://ncbi.nlm.nih.gov/pubmed/24597747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-12-59
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