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Human umbilical cord mesenchymal stromal cells suppress MHC class II expression on rat vascular endothelium and prolong survival time of cardiac allograft

Background: Human umbilical cord mesenchymal stromal cells (UC-MSCs) have low immunogenicity and immune regulation. To investigate immunomodulatory effects of human UC-MSCs on MHC class II expression and allograft, we transplanted heart of transgenic rats with MHC class II expression on vascular end...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Qiu, Ying, Yun, Mark M, Han, Xia, Zhao, Ruidong, Zhou, Erxia, Yun, Sheng
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132141/
https://ncbi.nlm.nih.gov/pubmed/25126177
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