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Involvement of the Carboxyl-Terminal Region of the Yeast Peroxisomal Half ABC Transporter Pxa2p in Its Interaction with Pxa1p and in Transporter Function

BACKGROUND: The peroxisome is a single membrane-bound organelle in eukaryotic cells involved in lipid metabolism, including β-oxidation of fatty acids. The human genetic disorder X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ABCD1 gene (encoding ALDP, a peroxisomal half ATP-bin...

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Autors principals: Chuang, Cheng-Yi, Chen, Ling-Yun, Fu, Ru-Huei, Chen, Shih-Ming, Ho, Ming-Hua, Huang, Jie-Mau, Hsu, Chia-Chi, Wang, Chien-Cheng, Chen, Meng-Shian, Tsai, Rong-Tzong
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132065/
https://ncbi.nlm.nih.gov/pubmed/25118695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104892
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