Dissecting the Regulatory Microenvironment of a Large Animal Model of Non-Hodgkin Lymphoma: Evidence of a Negative Prognostic Impact of FOXP3(+) T Cells in Canine B Cell Lymphoma

The cancer microenvironment plays a pivotal role in oncogenesis, containing a number of regulatory cells that attenuate the anti-neoplastic immune response. While the negative prognostic impact of regulatory T cells (Tregs) in the context of most solid tissue tumors is well established, their role i...

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Main Authors: Pinheiro, Dammy, Chang, Yu-Mei, Bryant, Hannah, Szladovits, Balazs, Dalessandri, Tim, Davison, Lucy J., Yallop, Elizabeth, Mills, Emily, Leo, Chiara, Lara, Ana, Stell, Anneliese, Polton, Gerry, Garden, Oliver A.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132014/
https://ncbi.nlm.nih.gov/pubmed/25119018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105027
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