Origin recognition specificity in pT181 plasmids is determined by a functionally asymmetric palindromic DNA element.

The leading strand replication origin of pT181 plasmids consists of two adjacent inverted repeat elements (IR-II and IR-III), which are involved in origin recognition by the initiator (Rep) protein. The conserved core element, IR-II, which contains the initiation nick site, is induced by Rep to form...

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Bibliografiske detaljer
Udgivet i:EMBO J
Main Authors: Wang, P Z, Projan, S J, Henriquez, V, Novick, R P
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1993
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC413174/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8428593/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1993.tb05630.x
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