SOD1(G93A) transgenic mouse CD4(+) T cells mediate neuroprotection after facial nerve axotomy when removed from a suppressive peripheral microenvironment

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease involving motoneuron (MN) axonal withdrawal and cell death. Previously, we established that facial MN (FMN) survival levels in the SOD1(G93A) transgenic mouse model of ALS are reduced and nerve regeneration is delayed, similar...

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Main Authors: Mesnard-Hoaglin, Nichole A., Xin, Junping, Haulcomb, Melissa M., Batka, Richard J., Sanders, Virginia M., Jones, Kathryn J.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4131730/
https://ncbi.nlm.nih.gov/pubmed/24911596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2014.05.019
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