Pachymic Acid Enhances Pentobarbital-Induced Sleeping Behaviors via GABA(A)-ergic Systems in Mice

This study was investigated to know whether pachymic acid (PA), one of the predominant triterpenoids in Poria cocos (Hoelen) has the sedative-hypnotic effects, and underlying mechanisms are mediated via γ-aminobutyric acid (GABA)-ergic systems. Oral administration of PA markedly suppressed locomotio...

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Autors principals: Shah, Vikash Kumar, Choi, Jae Joon, Han, Jin-Yi, Lee, Mi Kyeong, Hong, Jin Tae, Oh, Ki-Wan
Format: Artigo
Idioma:Inglês
Publicat: The Korean Society of Applied Pharmacology 2014
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4131518/
https://ncbi.nlm.nih.gov/pubmed/25143810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2014.045
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