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The significance of the F variant of alpha-1-antitrypsin and unique case report of a PiFF homozygote
BACKGROUND: Inheritance of the F variant of alpha-1-antitrypsin is associated with normal circulating protein levels, but it is believed to be dysfunctional in its ability to inhibit neutrophil elastase and therefore has been implicated as a susceptibility factor for the development of emphysema. In...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4131482/ https://ncbi.nlm.nih.gov/pubmed/25098359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2466-14-132 |
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