Alpha II Spectrin Breakdown Products in Immature Sprague Dawley Rat Hippocampus and Cortex after Traumatic Brain Injury

After traumatic brain injury (TBI), proteolysis of Alpha II Spectrin by Calpain 1 produces 145 SBDPs (Spectrin Breakdown Products) while proteolysis by Caspase 3 produces 120 SBDPs. 145 and 120 SBDP immunoblotting reflects the relative importance of caspase-dependent apoptosis or calpain-dependent e...

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Autores principales: Schober, Michelle E, Requena, Daniela F, Davis, Lizeth J, Metzger, Ryan, Bennett, Kim, Morita, Denise, Niedzwecki, Christian, Yang, Zhihui, Wang, Kevin K W
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4131452/
https://ncbi.nlm.nih.gov/pubmed/24929209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2014.05.046
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