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Physicochemical properties of EGF receptor inhibitors and development of a nanoliposomal formulation of gefitinib
Inhibitors of epidermal growth factor (EGF) receptor tyrosine kinases show efficacy in cancers that are highly addicted to non-mutated EGF signaling, but off-target effects limit therapy. Carrier-based formulations could reduce drug deposition in normal tissues, enhance tumor deposition, and reduce...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4131431/ https://ncbi.nlm.nih.gov/pubmed/22581704 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.23180 |
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