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Ubiquitination by SAG regulates macrophage survival/death and immune response during infection

The checkpoint between the life and death of macrophages is crucial for the host's frontline immune defense during acute phase infection. However, the mechanism as to how the immune cell equilibrates between apoptosis and immune response is unclear. Using in vitro and ex vivo approaches, we sho...

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Detalhes bibliográficos
Main Authors: Chang, S C, Ding, J L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4131172/
https://ncbi.nlm.nih.gov/pubmed/24786833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.54
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