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Osteopontin knockdown suppresses the growth and angiogenesis of colon cancer cells

AIM: To investigate the effects of osteopontin (OPN) gene expression knockdown on colon cancer Lovo cells in vitro. METHODS: Four candidate small interfering RNA (siRNA) constructs targeting the OPN gene and a scrambled control sequence (NC-siRNA) were synthesized and inserted into a pGPU6/GFP/Neo e...

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Bibliografiska uppgifter
Huvudupphovsmän: Wu, Xin-Lin, Lin, Kai-Jin, Bai, Ai-Ping, Wang, Wan-Xiang, Meng, Xing-Kai, Su, Xiu-Lan, Hou, Ming-Xing, Dong, Pei-De, Zhang, Jun-Jing, Wang, Zhao-Yang, Shi, Lin
Materialtyp: Artigo
Språk:Inglês
Publicerad: Baishideng Publishing Group Inc 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4130851/
https://ncbi.nlm.nih.gov/pubmed/25132760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v20.i30.10440
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