Loss of Growth Arrest Specific Gene 6 (Gas6) Results in Altered GnRH Neuron Migration, Delayed Vaginal Opening and Sexual Maturation in Mice

Prior work has shown the importance of TAM (Tyro3, Axl, Mer) receptor tyrosine kinases in GnRH neuronal development and reproductive function. It is unclear if TAM receptor actions are dependent on ligand activation for their functional effects; thus, we characterized reproductive phenotype of ligan...

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Huvudupphovsmän: Salian-Mehta, Smita, Xu, Mei, Pierce, Angela, Bliesner, Brian, Tobet, Stuart, Wierman, Margaret E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4130768/
https://ncbi.nlm.nih.gov/pubmed/24978606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2014.06.015
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