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Pharmacokinetics of co-formulated mefloquine and artesunate in pregnant and non-pregnant women with uncomplicated Plasmodium falciparum infection in Burkina Faso

OBJECTIVES: Mefloquine/artesunate has recently been developed as a fixed-dose combination, providing a promising rescue/alternative treatment for malaria during pregnancy. However, limited data are available on the effect of pregnancy on its pharmacokinetic properties. This study was conducted to as...

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Autors principals: Valea, Innocent, Tinto, Halidou, Traore/Coulibaly, Maminata, Toe, Laeticia C., Lindegardh, Niklas, Tarning, Joel, Van Geertruyden, Jean-Pierre, D'Alessandro, Umberto, Davies, Geraint R., Ward, Stephen A.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4130382/
https://ncbi.nlm.nih.gov/pubmed/24891429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dku154
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