The immunogenicity and protection effect of the BPL-inactivated CA16 vaccine in different animal systems

We evaluated the effect of a β-propiolactone (BPL)-inactivated coxsackievirus A16 (CA16) vaccine, using three immunogenicity evaluation and two animal challenge systems. A CA16 virus strain, named 419, was used as the production strain. Another CA16 strain, named 1131, was isolated and used as the c...

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Bibliographic Details
Main Authors: Qi An, Wen, Guo Su, Zhi, Wen Pan, Ruo, Ping Yang, Bao, Chao Zhang, Yong, Shi, Liang, Li, Qing
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2014
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4130287/
https://ncbi.nlm.nih.gov/pubmed/24401488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.27295
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