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Interferon, double-stranded RNA, and RNA degradation: activation of an endonuclease by (2'-5')An.

Among the mediators of interferon action are one enzyme that is activated by double-stranded RNA to convert ATP to (2'-5')An and a second enzyme, an endonuclease, that is activated by (2'-5')An to cleave single-stranded RNA. The binding of (2'-5')An to the endonuclease (partially purified from mouse...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Slattery, E, Ghosh, N, Samanta, H, Lengyel, P
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1979
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC413020/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/291897/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.10.4778
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