BRCA-Associated Ovarian Cancer: From Molecular Genetics to Risk Management

Ovarian cancer (OC) mostly arises sporadically, but a fraction of cases are associated with mutations in BRCA1 and BRCA2 genes. The presence of a BRCA mutation in OC patients has been suggested as a prognostic and predictive factor. In addition, the identification of asymptomatic carriers of such mu...

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Detalhes bibliográficos
Main Authors: Girolimetti, Giulia, Perrone, Anna Myriam, Santini, Donatella, Barbieri, Elena, Guerra, Flora, Ferrari, Simona, Zamagni, Claudio, De Iaco, Pierandrea, Gasparre, Giuseppe, Turchetti, Daniela
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Review Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4129974/
https://ncbi.nlm.nih.gov/pubmed/25136623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/787143
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