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Autophagy Reduces Acute Ethanol-Induced Hepatotoxicity and Steatosis in Mice

BACKGROUND & AIMS: Alcohol abuse is a major cause of liver injury. The pathologic features of alcoholic liver disease develop over prolonged periods, yet the cellular defense mechanisms against the detrimental effects of alcohol are not well understood. We investigated whether macroautophagy, an...

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Detalhes bibliográficos
Main Authors: Ding, Wen-Xing, Li, Min, Chen, Xiaoyun, Ni, Hong-Min, Lin, Chie-Wen, Gao, Wentao, Lu, Binfeng, Stolz, Donna B, Clemens, Dahn L., Yin, Xiao-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4129642/
https://ncbi.nlm.nih.gov/pubmed/20659474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2010.07.041
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