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Inhibition of amyloid precursor protein secretases reduces recovery after spinal cord injury
Amyloid-β (Aβ) is produced through the enzymatic cleavage of amyloid precursor protein (APP) by β (Bace1) and γ -secretases. The accumulation and aggregation of Aβ as amyloid plaques is the hallmark pathology of Alzheimer’s disease and has been found in other neurological disorders, such as traumati...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4129635/ https://ncbi.nlm.nih.gov/pubmed/24630972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2014.02.049 |
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