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The Validity of Quasi-Steady-State Approximations in Discrete Stochastic Simulations

In biochemical networks, reactions often occur on disparate timescales and can be characterized as either fast or slow. The quasi-steady-state approximation (QSSA) utilizes timescale separation to project models of biochemical networks onto lower-dimensional slow manifolds. As a result, fast element...

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Библиографические подробности
Главные авторы: Kim, Jae Kyoung, Josić, Krešimir, Bennett, Matthew R.
Формат: Artigo
Язык:Inglês
Опубликовано: The Biophysical Society 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4129492/
https://ncbi.nlm.nih.gov/pubmed/25099817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.06.012
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