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The Domain Interface of the Human Glutamate Transporter EAAT1 Mediates Chloride Permeation
The concentration of glutamate within the glutamatergic synapse is tightly regulated by the excitatory amino-acid transporters (EAATs). In addition to their primary role of clearing extracellular glutamate, the EAATs also possess a thermodynamically uncoupled Cl(−) conductance. Several crystal struc...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Biophysical Society
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4129490/ https://ncbi.nlm.nih.gov/pubmed/25099801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.05.046 |
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