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TENSION ON THE LINKER GATES THE ATP-DEPENDENT RELEASE OF DYNEIN FROM MICROTUBULES
Cytoplasmic dynein is a dimeric motor that transports intracellular cargoes towards the minus-end of microtubules (MTs). In contrast to other processive motors, stepping of the dynein motor domains (heads) is not precisely coordinated. Therefore, the mechanism of dynein processivity remains unclear....
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4129465/ https://ncbi.nlm.nih.gov/pubmed/25109325 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5587 |
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