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Viral infection controlled by a calcium-dependent lipid-binding module in ALIX

ALIX plays a role in nucleocapsid release during viral infection, as does lysobisphosphatidic acid (LBPA). However, the mechanism remains unclear. Here we report that LBPA is recognized within an exposed site in ALIX Bro1 domain predicted by MODA, an algorithm for discovering membrane-docking areas...

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Main Authors: Bissig, Christin, Lenoir, Marc, Velluz, Marie-Claire, Kufareva, Irina, Abagyan, Ruben, Overduin, Michael, Gruenberg, Jean
格式: Artigo
語言:Inglês
出版: 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4129370/
https://ncbi.nlm.nih.gov/pubmed/23664863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2013.04.003
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