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Delivering Nanoparticles to Lungs While Avoiding Liver and Spleen through Adsorption on Red Blood Cells

Nanoparticulate drug delivery systems are one of the most widely investigated approaches for developing novel therapies for a variety of diseases. However, rapid clearance and poor targeting limit their clinical utility. Here, we describe an approach to harness the flexibility, circulation, and vasc...

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Detalhes bibliográficos
Main Authors: Anselmo, Aaron C., Gupta, Vivek, Zern, Blaine J., Pan, Daniel, Zakrewsky, Michael, Muzykantov, Vladimir, Mitragotri, Samir
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4128963/
https://ncbi.nlm.nih.gov/pubmed/24182189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn404853z
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