Metformin inhibition of neuroblastoma cell proliferation is differently modulated by cell differentiation induced by retinoic acid or overexpression of NDM29 non-coding RNA

BACKGROUND: Metformin is a widely used oral hypoglycemizing agent recently proposed as potential anti-cancer drug. In this study we report the antiproliferative effect of metformin treatment in a high risk neuroblastoma cell model, focusing on possible effects associated to different levels of diffe...

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Autores principales: Costa, Delfina, Gigoni, Arianna, Würth, Roberto, Cancedda, Ranieri, Florio, Tullio, Pagano, Aldo
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2014
Materias:
Primary Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4128937/
https://ncbi.nlm.nih.gov/pubmed/25120382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-14-59
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