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Keap1 modulates the redox cycle and hepatocyte cell cycle in regenerating liver
Keap1 negatively controls the activity of transcription factor Nrf2. This Keap1/Nrf2 pathway plays a critical role in combating oxidative stress. We aimed at determining whether and how Keap1 modulates the cell cycle of replicating hepatocytes during liver regeneration. Two-thirds partial hepatectom...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4128880/ https://ncbi.nlm.nih.gov/pubmed/25483186 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.29298 |
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