Neuromelanin Magnetic Resonance Imaging Reveals Increased Dopaminergic Neuron Activity in the Substantia Nigra of Patients with Schizophrenia

PURPOSE: The dopamine hypothesis suggests that excessive dopamine release results in the symptoms of schizophrenia. The purpose of this study was to elucidate the dopaminergic and noradrenergic neurons using 3-T neuromelanin magnetic resonance imaging (MRI) in patients with schizophrenia and healthy...

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Detalhes bibliográficos
Main Authors: Watanabe, Yoshiyuki, Tanaka, Hisashi, Tsukabe, Akio, Kunitomi, Yuki, Nishizawa, Mitsuo, Hashimoto, Ryota, Yamamori, Hidenaga, Fujimoto, Michiko, Fukunaga, Masaki, Tomiyama, Noriyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4128756/
https://ncbi.nlm.nih.gov/pubmed/25111500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104619
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