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AGR2, an Endoplasmic Reticulum Protein, Is Secreted into the Gastrointestinal Mucus
The MUC2 mucin is the major constituent of the two mucus layers in colon. Mice lacking the disulfide isomerase-like protein Agr2 have been shown to be more susceptible to colon inflammation. The Agr2(−/−) mice have less filled goblet cells and were now shown to have a poorly developed inner colon mu...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4128659/ https://ncbi.nlm.nih.gov/pubmed/25111734 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104186 |
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